Cannabinoids and the endocannabinoid system (ECS) encompass both ancient and complex aspects of our biology. The endocannabinoid system exists in all vertebrate species, and may have begun evolving as early as 600 million years ago.
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The three most studied conditions linked to Clinical Endocannabinoid Deficiency (CED) are migraines, fibromyalgia, and Irritable Bowel Syndrome.
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THC, CBD and beta caryophyllene (a terpene present in cannabis) have all been shown to reduce pain.
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